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1.?Cao X, Ma L, Yang F, Wang K, Zheng J. Divalent cations potentiate TRPV1 channel by lowering the heat activation threshold. J Gen Physiol. 2014 Jan;143(1):75-90.

2.?Huang Z, Gibb AJ. Mg2+ block properties of triheteromeric GluN1-GluN2B-GluN2D NMDA receptors on neonatal rat substantia nigra pars compacta dopaminergic neurones. J Physiol. 2014 May 15;592(Pt 10):2059-78.

3.?Zhu Y, Bu Q, Liu X, Hu W, Wang Y. Neuroprotective effect of TAT-14-3-3ε fusion protein against cerebral ischemia/reperfusion injury in rats. PLoS One. 2014 Mar 26;9(3):e93334.

4.?Zhou BY, Yan SY, Shi WL, Qu Z, Zhao X, Liu ZM, Pu XP. Serum proteomic analysis reveals high frequency of haptoglobin deficiency and elevated thyroxine level in heroin addicts. PLoS One. 2014 Apr 17;9(4):e95345.

5.??Sun Y, Zhang WJ, Zhao X, Yuan RP, Jiang H, Pu XP. PARK7 protein translocating into spermatozoa mitochondria in Chinese asthenozoospermia. Reproduction. 2014 Sep;148(3):249-57.

6.??Tang YQ, Zhou JH, Yang F, Zheng J, Wang K. The tetramerization domain potentiates Kv4 channel function by suppressing closed-state inactivation. Biophys J. 2014 Sep 2;107(5):1090-104.

7.??Zheng XY, Yang YF, Li W, Zhao X, Sun Y, Sun H, Wang YH, Pu XP. Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo. J Ethnopharmacol. 2014 May 14;153(3):854-63.

8.??Bu Q, Liu X, Zhu Y, Liu Y, Wang Y. w007B protects brain against ischemia-reperfusion injury in rats through inhibiting inflammation, apoptosis and autophagy. Brain Res. 2014 Apr 16;1558:100-8.

9.??Wang YH, Yu HT, Pu XP, Du GH. Myricitrin alleviates methylglyoxal-induced mitochondrial dysfunction and AGEs/RAGE/NF-κB pathway activation in SH-SY5Y cells. J Mol Neurosci. 2014 Aug;53(4):562-70.

10.?Wang YH, Han YP, Yu HT, Pu XP, Du GH. Protocatechualdehyde prevents methylglyoxal-induced mitochondrial dysfunction and AGEs-RAGE axis activation in human lens epithelial cells. Eur J Pharmacol. 2014 Sep 5;738:374-83.

11.?Gao X, Yang H, Xu Y, Xiong Y, Wang G, Ye X, Ye J. Iminosugar derivative WGN-26 suppresses acute allograft rejection via inhibiting the IFN-γ/p-STAT1/T-bet signaling pathway. Int Immunopharmacol. 2014 Dec;23(2):688-95.

12.?Li M, Lei L, Jia L, Ling X, Zhang J, Zhao Y, Wang K. Interactions of KChIP4a and its mutants with Ca2+ or Kv4.3 N-terminus by affinity capillary electrophoresis. Anal Biochem. 2014 Mar 15;449:99-105.

13.?Deng Z, Zhou JJ, Sun SY, Zhao X, Sun Y, Pu XP. Procaterol but Not Dexamethasone Protects 16HBE Cells From H2O2-Induced Oxidative Stress. J Pharmacol Sci 2014 ;125 (1): ?39-50

14.?Zhu Y, Liu A, Liu X, Wang Y. Engineering novel anticoagulant proteins by motif grafting. Protein Pept Lett. 2014;21(2):159-63.


  1. Zhenyu Hu, Xiling Bian, Xiaoyan Liu, Yuanjun Zhu, Xiaoyi Zhang, Shizhong Chen, Kewei Wang, Yinye Wang (2013)Honokiol protects brain against ischemia-reperfusion injury in rats through disrupting PSD95-nNOS interaction. Brain Res. 1491:204-12. (IF 2.88)
  2. SuncanaSimonic-Kocijan, Xuehong Zhao, Wen Liu, Yuwei Wu, IvoneUhac, Kewei Wang (2013) TRPV1 channel-mediated bilateral allodynia induced by unilateral masseter muscle inflammation in rats. Molecular Pain. 9:68 (IF 3.77)
  3. DiJing Shi, Sheng Ye, Xu Cao, Rongguang Zhang and Kewei Wang (2013) Crystal structure of the N-terminal ankyrin repeat domain of TRPV3 reveals unique conformation offinger 3 loop critical for channel function, Protein &Cell 4(12):942-50. (IF 3.22)
  4. Yanxin Lu, Xupeng Yue, Yuanyuan Cui, Jufeng Zhang, Kewei Wang (2013) MicroRNA-124 suppresses growth of human hepatocellular carcinoma by targeting STAT3, Biochem Biophys Res Commun. 2013. 441(4):873-9
  5. Yiquan Tang, Ping Liang, Jingheng Zhou, Yanxin Lu, Lei Lei, Xiling Bian, Kewei Wang(2013) Auxiliary KChIP4a Suppresses A-type K+ Current through ER Retention and Promoting Closed-state Inactivation of Kv4 Channels, J Biol Chem. 288 (21):14727–41(IF 4.65)
  6. Lei Lei, Xu Cao, Fan Yang, DiJing Shi, Yiquan Tang, Jie Zheng, Kewei Wang (2013) A TRPV4 channel C-terminal folding recognition domain critical for trafficking and function, J Biol Chem, 288: 10427-39.(IF 4.65)
  7. Limin Shi, Xiling Bian, Zhiqiang Qu, Zegang Ma, Yu Zhou, KeWei Wang, Hong Jiang, JunxiaXie (2013) Peptide hormone ghrelin enhances neuronal excitability by inhibition of Kv7/KCNQ channels, Nat Commun. 4:1435. (IF 10.02)
  8. Weiwei Zhang, Qi Sun, Yimin Jiang, Runtao Li, Jia Ye. (2013) Anti-Inflammation of Spirocyclopiperazinium Salt Compound LXM-10 Targeting a7 nAChR and M4 mAChR and Inhibiting JAK2/STAT3 Pathway in Rats. PLoS One. 8(6):e66895. (IF 3.73)
  9. Xin Zhao, Shenyu Zhai, Mingsheng An, Yuehua Wang, Yingfan Yang, Huiqi Ge, Jinhao Liu, Xiaoping Pu (2013) Neuroprotective Effects of Protocatechuic Aldehyde against Neurotoxin-Induced Cellular and Animal Models of Parkinson’s Disease. PLoS One. 8(10):e78220. (IF 3.73)
  10. Peng Zhang, Xiaoyan Liu, Yuanjun Zhu, Shizhong Chen, Demin Zhou, Yinye Wang ( 2013) Honokiol inhibits the inflammatory reaction during cerebral ischemia reperfusion by suppressing NF-kB activation and cytokine production of glial cells, Neurosci Lett. 534:123-7. (IF 2.03)
  11. Xiling Bian (2013) Physiological and morphological character ization of GABAergic neurons in the medial amygdale. Brain Res. 1509:8-19. (IF 2.88)


  1. Wen Liu, Min Lu, Bogang Liu, Yi Huang, Kewei Wang(2012) Inhibition of Ca2+-activated Cl- channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma. Cancer Letters. 326:41-51 (IF 4.26)
  2. Xu Cao, Fan Yang, Jie Zheng and Kewei Wang (2012) Intracellular proton-mediated activationof TRPV3 channels accounts for exfoliation effect of alpha hydroxyl acids on keratinocytes. J Biol Chem. 287:25905-16 (IF 4.65)
  3. Yuanyuan Cui, Fan Yang, Xu Cao, Vladimir Yarov-Yarovoy, KeWei Wang, Jie Zheng(2012)Selective Disruption of High-Sensitivity Heat Activation but Not Capsaicin Activation of TRPV1 Channels by Pore Turret Mutations. J Gen Physiol. 139(4):273-83. (IF 4.73)
  4. Shuangyong Sun, Chunna An, Xiaoping Pu (2012) DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats. Brain Res Bull. 88(6):609-16. (IF 2.94)
  5. Shen Li, Yi Sun, Xin Zhao, Xiaoping Pu (2012) Expression of the Parkinson's disease protein DJ-1 during the differentiation of neural stem cells. Brain Res. 1468:84-93. (IF 2.88)
  6. Wanlu Shi, Xin Zhao, Zhimin Liu, Min Zhang, Bingying Zhou, Xiaoping Pu (2012) Serum proteomics of methamphetamine addicts and up-regulation of complement factor H related to methamphetamine addiction. Neurosci Lett. 525(1):23-8. (IF 2.03)


  1. Qianqian Wang, Xin Zhao, Xiaoping Pu (2011) Proteome analysis of the left ventricle in the vitamin Dand nicotine-induced rat vascular calcification model. J Proteomics. 74(4):480-9. (IF 4.88)
  2. Chunna An, Hui Jiang, Qi Wang, , Renpei Yuan, Jianming Liu, Wanlu Shi, Ziyu Zhang, Xiaoping Pu (2011) Down-regulation of DJ-1 protein in the ejaculated spermatozoa from Chinese asthenozoospermia patients. Fertil Steril. 96(1):19-23. (IF 3.56)
  3. Qian Wu, Yongh Zhang, Xin Zhao, WanluShi, Xiaoping Pu (2011) proteome studies on liver tissue in a phemobarbital-induced rat model. Eur J Pharmacol. 670(2-3):333-40. (IF 2.52)
  4. Xia Zhao, Jia Ye, Qi Sun, Yulan Xiong, Runtao Li, Yimin Jiang (2011)Antinociceptive effect of spirocyclopiperazinium salt compound LXM-15 via activating peripheral α7 nAChR and M4 mAChR in mice. Neuropharmacology. 60(2-3):446-52. (IF 4.81)
  5. Yeping Bi, Hui Chen, Jun Su, Xu Cao, Xiling Bian and Kewei Wang (2011) Visceral hyperalgesia induced by forebrain-specific suppression of native Kv7/KCNQ/M-current in mice. Molecular Pain 7:84 (IF 3.53)
  6. Jun Su, Xu Cao and Kewei Wang (2011) A novel degradation signal derived from distal C-terminal frame-shift mutations of KCNQ2 which cause neonatal epilepsy. J Biol Chem. 286 (50):42949-58 (IF 4.77)
  7. Feng Zhang, Shuang Liu, Fan Yang, Jie Zheng and Kewei Wang (2011) Identification of a tetrameric assembly domain in the C-terminus of heat-activated TRPV1 channels, J Biol Chem. 286(17):15308–16 (IF 4.77)


  1. Wen Xu, Yuwei Wu, Yeping Bi, Lei Tan, YehuaGan and KeWei Wang(2010) Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats. Mol Pain 6:49 (IF 4.15)
  2. Ping Liang, Hao Chen, Yuanyuan Cui, and KeWei Wang (2010) Functional Rescue of Kv4.3 Channel Tetramerization Mutants by KChIP4 Biophys J 98 (12):2867-76. (IF 4.22)
  3. Hong Sun, Qingming Che, Xin Zhao, Xiaoping Pu (2010) Antibrotic effects of chronic baicalein administration in a CCl4 liver brosis model in rats. Eur J Pharmacol. 631(1-3):53-60. (IF 2.59)
  4. Yulan Xiong, Xia Zhao, Qi Sun, Runtao Li, Changling Li, Jia Ye (2010) Antinociceptive mechanism of the spirocyclopiperazinium compound LXM-10 in mice and rats. Pharmacol Biochem Behav. 95(2):192-7. (IF 2.97)
  5. Yulan Xiong, Jia Ye, Qi Sun, Xia Zhao, Runtao Li, Yimin Jiang (2010) Anti-inflammatory effect of the spirocyclopiperazinium compound LXM-10 in mice and rats. Eur J Pharmacol. 626(2-3):290-6. (IF 2.59)